Recently the news reported on a study which suggested that one reason why Asians are more prone to diabetes is due to inadequate insulin production.
Local researchers from the National University Hospital (NUH), in collaboration with Janssen Pharmaceuticals, have found that the inability to produce enough insulin could be why Asians are more prone to Type 2 diabetes than their Western counterparts.
The breakthrough finding, based on a study of 140 mostly Chinese participants, will pave the way for better diabetes management for people here and in the region. This includes tailoring dietary advice and a better selection of drugs to treat diabetes, doctors believe.
Another interesting finding from a separate study is that Chinese people are more prone to diabetes at lower BMIs than Caucasians.
According to a previous study, 8 per cent of people of Chinese descent with a Body Mass Index (BMI) of 23 (just outside the healthy weight range) have diabetes. This is four times more than their European counterparts. A BMI of 23 is within the normal weight range for Caucasians.
As I have mentioned in my previous blog post, Caucasians tend to have lower body fat than Asians despite having the same BMI.
Although Asians had lower BMI, they were fatter than whites of both sexes. The correlations between fat% and BMI varied by BMI and sex and race. Comparisons in anthropometry show that Asians had more subcutaneous fat than did whites and had different fat distributions from whites. Asians had more upper-body subcutaneous fat than did whites. The magnitude of differences between the two races was greater in females than in males.
My theory is that the impaired insulin production is due to the higher body fat percentage that Asians seem to have. A higher body fat percentage translates to a lower fat free mass. Which in turn reduces insulin production. Hence in comparison to Caucasians with the same BMI but lower body fat percentage, Asians will produce less insulin.
This news outlet reported on the same article, but I disagree with something they added.
In a separate study, it was also discovered that 8 per cent of Chinese participants with a Body Mass Index (BMI) of 23 (this means they’re just outside the healthy range) have diabetes, four times more than those of European descent.
The reason for this? Caucasians generally have more body fat and therefore, a BMI of 23 is considered normal for them.
The part that is in bold is incorrect. The opposite is true, Asians in general have MORE body fat. That is the reason why WHO recommended a LOWER BMI cutoff for Asians.
On the basis of the available data in Asia, the WHO expert consultation concluded that Asians generally have a higher percentage of body fat than white people of the same age, sex, and BMI. Also, the proportion of Asian people with risk factors for type 2 diabetes and cardiovascular disease is substantial even below the existing WHO BMI cut-off point of 25 kg/m2. Thus, current WHO cut-off points do not provide an adequate basis for taking action on risks related to overweight and obesity in many populations in Asia.